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Predicted no-effect concentration : ウィキペディア英語版 | Predicted no-effect concentration The Predicted No Effect Concentration (PNEC) is the concentration of a chemical which marks the limit at which below no adverse effects of exposure in an ecosystem are measured. PNEC values are intended to be conservative and predict the concentration at which a chemical will likely have no toxic effect. They are not intended to predict the upper limit of concentration of a chemical that has a toxic effect.〔European Chemicals Bureau. 2003. Technical Guidance Document on Risk Assessment. European Communities. Available online at: https://echa.europa.eu/documents/10162/16960216/tgdpart2_2ed_en.pdf〕〔Predicted No Effect Concentration. 2015. Greenfacts. Available online at: http://www.greenfacts.org/glossary/pqrs/PNEC-predicted-no-effect-concentration.htm〕〔Lei BL, Huang SB, Jin XW, Wang Z. 2010. Deriving the aquatic predicted no-effect concentrations (PNECs) of three chlorophenols for the Taihu Lake, China. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 45(14):1823-31〕 PNEC values are often used in environmental risk assessment as a tool in ecotoxicology.〔〔〔Manuilova, A. 2003. Methods and Tools Available for Assessment of Environmental Risk. Dantes. Available online at: http://www.dantes.info/Publications/Publication-doc/An%20overview%20of%20ERA%20-methods%20and%20tools.pdf〕 A PNEC for a chemical can be calculated with acute toxicity or chronic toxicity single-species data, Species Sensitivity Distribution (SSD) multi-species data, field data or model ecosystems data. Depending of the type of data used, an assessment factor is used to account for the confidence of the toxicity data being extrapolated to an entire ecosystem.〔〔http://echa.europa.eu/documents/10162/0645f0cb-7880-4d23-acea-27b05ed7de39〕 ==Calculation Methods==
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